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Advanced Training Course on Radiation Emergency Medical Preparedness and Assistance
(Novel Medical Approaches in Radiation Accident Management

Theodor M. Fliedner (Director)

Radiation Medicine Research Group and WHO Collaborating Center for Radiation Accident Management, ICAS-Secretariat

 

The newly established International Center for Advanced Studies in Health Sciences and Services at the University of Ulm is preparing for 2003 or 2004 (depending on financial support from the European Commission) an Advanced Training Course focusing on Novel Medical Approaches in Radiation Accident Management.

 This course is prompted by the observation that larger or smaller radiation accidents are likely any time and anywhere in Europe. Particularly, the enlargement of the European Communities and the fact of open borders with unlimited desirable and undesirable movements of people increases the probability of radiation accidents in the European region. They may be caused (increasingly observed) by radiation sources that are unrecognised when they are found in metal scrap places or used in criminal actions. Of course not only the built-up of nuclear facilities but also their maintenance as well as their removal carry a definite risk of radiation emergencies with potential health consequences.
It is also recognised that the medical profession across Europe is usually not updated in the recent approaches that have been developed to recognise, to diagnose and to treat radiation medical emergencies. Therefore, this course is specifically designed for medical doctors who carry responsibility in the area of radiation emergency planning and response action or who might become engaged in the medical handling of radiation accident victims. The present worldwide radiation emergency experience will be reviewed, the most recent diagnostic approaches discussed as well as therapeutic options outlined. Practical laboratory exercises will be performed to provide participants with up-to-date techniques. It can be anticipated that the participation in the course will be recognised by a certificate of the European Accreditation Council for Continuing Medical Education (EACCME).

Session I of this course is directed to an overview on radiation accident developments in the last 20-25 years. An update will be made as to the "classical" acute radiation syndrome. Thereafter, radiation accident experience will be presented and discussed after chronic or protracted radiation exposure. On this basis a large segment will be devoted to predominantly skin exposure as well as exposure by radionuclide contamination or incorporation.

Session II will deal with the medical management of radiation emergencies. This includes organisational and institutional prerequisites and the available international as well as national networks for help in case of radiation emergencies. Most of the European countries do have such national networks. It will be of interest to compare the potentialities of these networks to deal with recent development in radiation accident management. Also the potentialities of worldwide networks, such as established by the World Health Organization, will be discussed.

In Session III the pathophysiology of the response of the organism in case of acute, protracted or chronic radiation exposure will be discussed and updated. The haematopoietic system, the skin, the gastrointestinal tract as well as the neurovascular system are the most critical organs in dealing with accidentally radiation-exposed persons.

Session IV will discuss the most recent diagnostic approaches to radiation emergencies. It is pointed out that a west-European consortium supported by the European Communities developed the "METREPOL" approach (Medical Treatment Protocols for Radiation Accident Victims as a Basis for a Computerised Guidance System). On this basis, a grading code for the severity of damage of the organism was developed on the basis of indicators of radiation exposure, effects and repair. Also the response of the blood cell forming tissues will be discussed to assess the severity of effect. Furthermore, the role of cytogenetic indicators will be demonstrated and discussed in depth.

Session V will deal with therapeutic options for the acute radiation syndrome, for the chronic radiation syndrome, for skin lesions, for options in radionuclide contamination and for treatment options after incorporation of radionuclides.

In Session VI there will be practical exercises in order to understand what indicators are available to determine radiation exposure at the molecular level, the cellular level, the cell system level and the organ system level. In this context, use will be made of the SEARCH database (System for Evaluation and Archiving of Radiation Accidents based on Case Histories). This is a database containing more than 800 case histories of radiation accidents since 1945. The use of this database will provide valuable information for teaching purposes as well as for comparing new radiation accident case developments with historical ones. In the practical exercises, decontamination and decorporation approaches will be reviewed.

It is hoped that the European Late Effects Project Group will support such a course and will particularly support its funding by the European Communities.

For  further  Information
Prof. Dr. Theodor M. Fliedner
Director, Radiation Medicine Research Group and WHO Collaborating Center for Radiation Accident Management
ICAS-Secretariat
University of Ulm
Helmholtzstrasse 20
D-89081 Ulm
GERMANY

Phone: +49-731-500-22900/-22901
Fax:  +49-731-500-22902
e-mail: theodor.fliedner@medizin.uni-ulm.de